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[PDF]Evaluation of selenium effect on cadmium genotoxicity in Vicia faba using RAPD

 

Author: M. Sinan Taspinar 1, Guleray Agar 2*, Nalan Yildirim 2, Serap Sunar 2, Ozkan Aksakal 2 and Sedat Bozari 2

 

Received 17 June 2009, accepted 11 October 2009.

Abstract

 

In this study, the protective role of selenium (Se4+) against cadmium (Cd2+) toxicity induced DNA damage was determined by using RAPD. The results showed that all doses of Cd2+ caused an increase in polymorphism value and a decrease in genomic template stability (GTS %). In addition, when 0.08, 8 and 800 ppm concentrations of Se4+ were added, cadmium polymorphism value decreased and GTS increased. Results suggested that Se4+ has an antagonistic effect against Cd2+ and the degree of antagonistic effect of selenium against Cd2+ is probably related to its concentration ratio.

 

Key words: Cadmium, selenium, genotoxicity, RAPD.

[FULL text for subscribers]

Journal: Food, Agriculture & Environment (JFAE)
Online ISSN: 1459-0263
Year: 2009, Vol. 7, Issue 3&4, pages 857-860.
Publisher: WFL

 


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